Cosmetics 2014, 1(2), 105-116

Cosmetics 2014, 1(2), 105-116

Autori: Adele Sparavigna1, Beatrice Tenconi1, Ileana De Ponti1, Giancarlo Guglielmini2

1DermIng S.r.l. Clinical Research Institute, Viale Cesare Battisti 38, 20900 Monza, Italy, 2Sinerga SpA, Via della Pacciarna 67, 21050 Gorla Maggiore, Italy

Abstract: The aim of this study was to evaluate clinically and by non invasive instrumental evaluations the efficacy and tolerability of a cosmetic treatment containing an innovative active ingredient, ethyl ximenynate, in the prevention of dark circles under the eyes and blemishes of skin aging on the eye profile. Evaluations were performed at baseline and after 2 and 4 weeks of treatment on 22 volunteers; the study was planned as a double blind half-face trial. Data showed a trend towards a lifting of the eyelid skin; all investigator scores (eye puffiness, skin smoothness, roughness and dryness) decreased. In addition, profilometric results confirmed the anti-wrinkles efficacy of the active product and its lifting action, while those related to spectrophotometry underlined the decongestant effect on dark circles that appeared, at the end of the study, to be less marked. The improvement of skin microcirculation and capillary resistance and vascular tone in the eye area underlines a general mitigation of all relevant skin imperfections and blemishes of skin aging on the eye profile. The active ingredient was shown to be effective for the cosmetic treatment of the periocular area.